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Most studies have focused on the peel or the flesh extract of the fruit.
The most effective doses of flesh extract were 10 and 20 μl per 4 mL of cell culture medium.
In conclusion, the methanolic flesh extract of G. dulcis has demonstrated promising anticancer properties against liver cancer.
The flesh extract of G. dulcis induced cell cycle arrest at sub-G1 (apoptosis) phase in a time-dependent manner.
Allicin and alliin concentration were significantly higher in garlic flesh extract when compared to the skin extract.
Apoptosis and cell cycle arrest in HepG2 cancer cell were studied after exposure to G. dulcis flesh extract at IC50 concentration for 24, 48, and 72 hours.
Similar(45)
Here we report a ciguatoxin rapid extraction method (CREM) that allows the rapid preparation of fish flesh extracts for the detection and quantification of ciguatoxin by gradient reversed-phase liquid chromatography-tandem mass spectrometry (LC/MS/MS).
Skin and flesh extracts of purple variety of garlic is beneficial in preventing cardiomyocyte hypertrophy and cell death.
Norepinephrine (NE) was used to induce hypertrophy in adult rat cardiomyocytes pretreated with garlic skin and flesh extracts.
The skin and flesh extracts were also beneficial in preventing oxidative stress, the genesis of above mentioned deleterious process.
A dose dependent effect of garlic extracts were observed wherein, only the 20 μl dose of garlic skin and flesh extracts prevented this increase in cell death.
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