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The genomic regions flanking up to 2 kb (0 – 2 kb from CGI) that do not overlap with nearby CGIs were defined as CGI shores.
So far, these studies emphasized the presence of short (≤15 nt) cis-regulatory elements flanking up to 100 nt upstream the PASs.
The genomic regions flanking up to 2 kb from CGI shores (2 - 4 kb from CGI), that do not overlap with nearby CGIs and CGI shores are defined as CGI shelves [ 34, 62].
The sRNAs are shown by red arrows whereas green arrows indicate the flanking up and downstream genes.
Similar(56)
A key role in this glacially-controlled landscape system is played by the slope moraines, which cover the valley flanks up to several hundred meters above the valley floor.
The VSG117 cassette is inserted downstream of the puromycin drug resistance gene, which is flanked up and downstream by α-tubulin gene RNA processing signals [54].
The TOR sequence and flanking regions (up to 100 kb) were extracted from corresponding contigs or chromosomal sequences.
We only included OR genes whose sequences and flanking regions (up to 500 nucleotides) were not identical.
We have excluded regions flanking genes up to a distance of 10 kb, as reads in these regions are more frequent and possibly correlated with known genes.
When a segment of the Galileo TPase was used as the query subject, to identify TIRs and target site duplications (TSDs), pairwise comparisons of upstream and downstream flanking sequences (up to 5000-bp, if available) were carried out.
These aberrant empty sites are often the only mutations over a long stretch of flanking sequences (up to 1 kb), suggesting that they may have resulted from the transposition activity of ATons.
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