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B-mode imaging confirmed the difference in thickness between the lesion segment and flank segments of the phantom.
This new framework is based on multi-part injection molding principles that sequentially casted the lesion segment and the flank segments of the vessel model using molding parts devised with computer-aided design tools.
Also, Doppler-based vessel wall displacement analysis revealed that when pulsatile flow was fed through the phantom (carotid pulse; 27 mL/s peak flow rate), the lesion segment distended less compared with the flank segments.
Specifically, the three-beat averaged peak wall displacement in the lesion segment was measured as 0.28 mm, and it was significantly smaller than that of the flank segments (0.60 mm).
As a case demonstration, we fabricated a stenosed three-segment phantom composed of a central lesion segment (5.1-mm diameter, 1.95-mm wall thickness, 212.6-kPa elastic modulus) and two flank segments (6.0-mm diameter, 1.5-mm wall thickness, 133.7-kPa elastic modulus).
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A typical metazoan pri-miRNA consists of a stem of ∼33 bp, with a terminal loop and flanking segments.
The donor amplicon carries the mutant sequence and extensive flanking segments of homology, which ensure efficient and precise integration by the recombination machinery specific to competent cells.
Based on the presence of proline residues in the flanking segments of protein protein interaction sites, we predicted the site between 52PP56 to be the potential interaction site of bukatoxin.
Mimicking the interaction between amphiphilic S1P and its binding proteins, a series of polymers with hydrophilic poly ethylene glycol) core and lipophilic flanking segments of polylactide and/or poly alkylated lactide) with different alkyl chain lengths were synthesized.
αM2-cap residues exhibit higher Φ values than their flanking segments.
Tests for double events were made between the recombinant segment topology and each of the two topologies derived from the flanking segments independently.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com