In the 1960s, Gurdon [ 14] challenged the view of permanently fixed cell fates by showing that transfer of a somatic cell nucleus into an enucleated frog egg could reprogram the somatic nucleus to a pluripotent state.
He said it was not his patriotism that was being tested but independence would fix the fate of future generations.
The NHS Trusts Development Authority says half its trusts are in financial trouble, along with many foundation trusts: all risk falling into the hands of these TSA dictators to fix their fate.
Their mistake is usually to express themselves through fixed forms, a fate that might also befall some of the ingenious constructions in the British pavilion.
As stem cells progress towards a fixed lineage, their fate becomes more restricted to give rise to a limited subset of cell types (multipotent) before they finally differentiate.
But by the mid-two-thousands Chinese basketball fans no longer felt the need to fix their fates to Yao.
Embryonic polarity of invertebrates, amphibians and fish is specified largely by maternal determinants, which fixes cell fates early in development.
Dementia is still seen as a personal problem, framed as one in which your fate is fixed by whether or not you are treated well by individual carers.
As they glance at each other in their unfamiliar hotel room, seeing each other as if for the first time, it is as if fate has fixed them up on a blind date, kept them blind for three decades and then finally whipped off the blindfold to let each see the grumpy, sagging oldster they're stuck with.
It is only when a blastocyst is formed, with its cavity and the two established cell lineages, that cell fate is fixed through the differential expression of tissue-specific transcription factors allocation [14], [15].
