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To determine if behavioral sensitization to cocaine requires the activation of NMDARs in DA neurons, we examined the progressive escalating locomotor response to a fixed cocaine dose given in a novel environment or in the home cage [23], [24].
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In June 2013, Contostavlos was "exposed" by the Sun on Sunday's Mazher Mahmood, aka the Fake Sheikh, in a front-page splash alleging she had fixed a cocaine deal for him.
I play devil's advocate: you're a public figure, a role model for children, you end up fixing a cocaine deal and they want to expose your wrongdoing, even if that involves a degree of entrapment.
Both the Camorra and the 'Ndrangheta have a history of fixing the cocaine market, tampering with their product to maximize profit, simulating scarcity to drive up value, and spreading it wherever they can.
Thus, the early performance tests were conducted before and were thus unaffected by self-administered cocaine on these sessions, because they were explicitly assessed for cocaine seeking within the fixed interval rather than a fixed ratio.
After 24 hours of cocaine exposure, cultures were fixed with 4% paraformaldehyde (Sigma) in PBS and permeabilized with 0.1% Triton X-100.
Bookmakers Labour had pledged to crack down fixed odd betting terminals, often described as the "crack cocaine" of the gambling industry.
In adulthood, rats were tested for self-administration of saccharin (sweet), maltodextrin (non-sweet), and cocaine (a potent drug of abuse) using fixed- and progressive-ratio schedules, and a concentration-response curve for each substance.
The man in question was a frequent user of fixed odds betting terminals (FOBTs), which have been described as the "crack cocaine" of gambling, allowing players to stake £100 every 20 seconds.
The man, referred to only as Customer A, was a frequent user of fixed odds betting terminals (FOBTs), which have been referred to as the "crack cocaine" of gambling.
Cocaine-exposed (prenatal days 1 20, 30 mg/kg/day) rat pups were sedated and imaged live using diffusion tensor imaging and postmortem (fixed) using magnetic resonance histology on postnatal day 14.
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