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We have designed a device for long-term head fixation for use in behaving nonhuman primates that is robust yet minimally invasive and simple to use.
This would have implications for external fixation but would revolutionize internal fixation for use over a site of previous pin use and for routine use as a prophylactic measure against infection.
Previous work on the development of a new form of skin fixation for use with the CA 6000 has been fully described [ 1].
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The relatively short mean follow-up period in such a small number of cases, the lack of alternatives (different types of osteotomy and different fixation methods) for use as a control group, and the absence of any biomechanical lab studies comparing different fixation methods under different loading conditions are limitations of this study.
To extend the practical usage of the presented design, the proposed strategy has been utilized to control an auxiliary adjuster for stereotactic frame fixation system for use in the precise clinical neurosurgery operation.
We designed a globe-fixation system for use with animal eyes for surgical skills training.
Embryos were scored live using bright-field imaging, or after fixation for axon tracts using scanning confocal imaging.
Therefore, it has been suggested that bicortical fixation should be reserved for use in the sacrum or in cases where the additional fixation achieved is desperately needed [ 33].
The measure of spindle length in different conditions was performed using the Volocity 4.1 software (Improvision) to have a 3D reconstruction of spindles after fixation (for this we used the Z-stack obtained on the Leica SP5 confocal microscope).
Before permanent fixation, for example by using a plate, bone segments have to be positioned in the right relative alignment.
Special care was taken with the brain fixation for histochemistry assays, using non-crosslinking fixation to avoid denaturing the protein.
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