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The process of adduction and fixation of mutation and persistence of the mutation require several steps, which could partly explain the apparent lag between increased detection of AFB1 albumin adducts (a short-term biomarker of exposure to aflatoxin) and increased detection of R249S in CFDNA (which may occur days or weeks after exposure).
The bias for HGT even takes the form of circular reasoning in a review stating that "the fixation and long-term persistence of horizontally transferred genes suggests (our emphasis) that they confer a selective advantage on the recipient organism" ([ 187], page 709).
The key traits are prudence and persistence.
His signature is focus and persistence.
Apparently, patience and persistence are family traits.
The task ahead requires effort and persistence.
This requires consistency and persistence.
We propose that M. tuberculosis has evolved its widespread, pathogenic lifestyle starting from a pool of STB-like mycobacteria by gaining additional virulence and persistence mechanisms through a potential combination of (i) loss of gene function, (ii) acquisition of new genes via horizontal gene transfer, (iii) interstrain recombination of gene clusters and (iv) fixation of SNPs.
It would take patience and persistence.
"It will take patience and persistence".
This job also requires patience and persistence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com