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On the basis of previous studies, it may be known how fixation affects the sample structure.
In addition, prolonged fixation affects the magnetic properties of the tissue (Shepherd et al. 2009).
In breast cancer, it has been reported that a delay to formalin fixation affects FISH results but not IHC scores [ 16].
The fixation affects the water mobility and signal intensities of tissues, thus making the discrimination of tissues difficult [ 8, 19, 20].
Here we show attentional load at fixation affects the spatial tuning of population receptive fields (pRFs) in early visual cortex (V1 3) using functional magnetic resonance imaging (fMRI).
These results correspond well to the report of Hashizume et al. [ 15], who showed that prolonged fixation affects HER2 IHC score in 2+ or 1+ breast cancer specimens.
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The phenotypic equilibrium predicted for both parental sexes is, like the probability of fixation, affected by selection against reproductive variance.
Finally, analysis of selective constraints supports the adaptive fixation of amino acid replacements after gene duplication mainly leading to GroEL3 and that this fixation affected functional sites involved in interaction with protein clients.
In order to investigate whether the type of stem fixation affected cup survival when both stem and cup were exchanged at the index revision, we performed a separate analysis including this variable (cemented or uncemented stem fixation) as a covariate.
We also investigated whether delay to formalin fixation or prolonged fixation time affects FISH results.
Specimen size, time to fixation and fixation duration affect the quality of RNA from FFPE archival samples (von Ahlfen et al, 2007).
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