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In such a world, evidently, one has to fix the state of things over the whole of the world at a time t, in order for events to be strictly determined, by the laws of nature, for any amount of time thereafter.
No matter what the "speed limit" on physical influences is, if we want the entire future of the world to be determined, then we will have to fix the state of things over all of space, so as not to miss out something that could later come in "from outside" to spoil things.
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Loss-of-function simulations were done by fixing the state of the node to 0; for gain-of-function simulations it was set to 1.
Mutations were modelled by fixing the state of a node at 0 (loss of function) or 2 (gain of function) throughout the simulations.
When the system is perturbed by fixing the state of such nodes, one can measure the activity of each output node being observed.
An alternative approach to the direct reversal of the initial damage involves fixing the state of one or more nodes that are not part of the original damage (see e.g. [ 34, 39]).
One alternative approach involves compensating for network damage by fixing the state of one or more initially unaffected nodes; this is possible in signal transduction networks, e.g. through gene manipulations, constitutive activation, or pharmacological interventions (see e.g. [ 46, 47]).
To fix the state space of the models, we assume that the N-state models have all N states present at stability.
In order to get some fix on the state of affairs at the publisher's 11 daily titles, I have therefore compared their sales in June 2014 with those just released for the first half of this year.
The upcoming vote on repeal of the ACA is likely to be a "clean" up-or-down vote on repeal, but whenever Congress gets around to fixing the state Medicaid provisions of the ACA, a fight will almost certainly erupt over contraceptive coverage, certainly as it applies to employees of religiously affiliated schools and hospitals.
That independence, however, is based on an incredibly limited legal definition that the FPPC hopes to fix for the state of California.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com