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The incubation of human mammary epithelial cells with 5 μmol/l genistein induced a fivefold increase in the level of TGF-β secretion [ 76].
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Previously, EPEC was reported to cause a threefold to fivefold increase in the levels of calpain in intestinal cells (Hardwidge et al., 2004).
To test whether larger amounts of the hydrocarbons trigger higher levels of aggression, we tested the response to a fivefold increase in the concentration of 15MeC35, using ants from two of the supercolonies (Lake Skinner [LS] and Cottonwood [CW]).
Even a fivefold increase in the price of raw uranium oxide has little impact on the price of nuclear power.
There was almost a fivefold increase in the number of laparoscopic myomectomies performed in 2016 compared to 2004 (Fig. 1).
One CBC investigation found a fivefold increase in the number of domestic violence cases reported by on-base military police, circa 2008.
Detection of a more modest 20% reduction required a fivefold increase in the number of reviewed records.
When compared to wt cells, the doa10Δ mutant showed a reduction in the levels of ergosterol (by 13%) with a concomitant fivefold increase in the ergosterol precursor lanosterol.
Of those, STAT3 showed a sixfold increase in Ins2Akita-WT and a fivefold increase in the Ins2Akita-KO group.
Consistent with J2-IP selecting for dsRNA, we observed a fourfold to fivefold increase in expression level (RPKMs) of annotated transposon/retrotransposon sequences, as well as a twofold to fourfold increase in the expression level (RPKMs) of tandem/inverted repeats.
Loss of EGR1 and PTEN coincided with a fivefold increase in steady state levels of activated Akt (pAkt).
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