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The kinetics of the KCNQ2 and KCNQ2/3 conductances were extracted from the recordings presented in this manuscript using double exponential curve fitting to the current traces recorded in the voltage-clamp mode.
Similar(59)
A double-exponential function was fitted to the current decay at −60 mV.
Hence, our findings largely fit to the current biological knowledge about TGF-β.
The rate of onset was calculated as a reciprocal of the time constant of exponential function fitted to the current rising phase.
Fitting to the assembled single-channel currents, we found that both currents had an equal inactivation time constant of τi≈10 ms at 100 mV, indicating that there were four β subunits per channel in those experiments.
In synaptosome recordings, latency or delay of action of Calindol was measured from the plot of NSCC current amplitude versus time (diary plot) using the interception of the line representing average NSCC current amplitude at 60 µM Ca2+ and the extrapolated exponential fitted to the NSCC current during inhibition by Calindol (see Figure 4C).
The Drosophila CLN3 protein shows considerable homology with the human and mammalian forms and can be fitted to the most current topology predictions.
The mean holding current in each condition was determined from Gaussian fits to the distribution of holding current values sampled from each epoch.
It remains an interesting theoretical exercise to demonstrate that this simplistic assumption fits to the Ebola data, including the current multi-country epidemic.
A single-exponential function was fitted to the normalized peak tail currents to obtain τact.
But in fact it isn't a particularly harmonious product fit to the current trends that Foursquare is encountering.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com