All preliminary simulations were performed using Berkley Madonna, while C++ was used for all spatial modeling, high throughput simulations, parameter fitting, sensitivity analyses, and video generation.
Fitting sensitivity, specificity and likelihood ratios simultaneously allows the identification of covariates that independently affect diagnostic or screening test results and distinguishes spectrum effect from spectrum bias.
Open image in new window Fig. 2 Differences between formula 3 and 4. In the situation of light component oil blended with heavy contaminated oil, Li et al. (2011) have concluded that the dry point is the most sensitive item according to the experimental data fitting and sensitivity analysis.
Various analysis techniques, such as optimization (data fitting) and sensitivity analysis, require repeated batch jobs of large numbers of simulation to obtain statistically valid results.
To explore the effect of imperfect diagnostic testing on model fitting test sensitivity was assumed (conservatively) to be just 50% (see Matthews et al., 2009 ) and on-farm prevalences, x, were accordingly transformed as (2 − x ) x (imperfect sensitivity ).
This raises the danger of over-fitting and sensitivity to model specification.
By simple linear fittings, the sensitivities of the five different kinds of sensors are derived, shown in Table 1.
We used the Microsoft Excel add-in @Risk, version 6.01 (Palisade Corporation, Ithaca, NY) for distribution fitting, fit testing, probabilistic risk assessments, and sensitivity analyses.
In fact, considering the whole amount of samples and comparing the values of indices calculated for each profile couple (real and artificial ones having the same ISO 8608 fitting parameters), the sensitivity of the three roughness evaluation approaches was found to be meaningfully different.
The use of optical method for measuring the front cavity volume has refined the measurement methodology followed with adaptation of a self reliant, traceable and systematic measurement procedure in comparison to the earlier use of nominal values for sensitivity fitting exercise conducted on MP.EXE program.
The flux distribution obtained from these investigations is displayed in Figure 5 and listed in Additional file 13, and the fitting accuracy and sensitivity analysis are listed in Additional files 12, 13, 14 and 15.
