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The comparative molecular field analysis and comparative molecular similarity analysis (CoMFA and CoMSIA, respectively) compute interaction energies in 3D grid points and then proceed by using a partial least squares fitting algorithm for pharmacophore models.
This procedure is based on a data fitting algorithm, for which the shape of the COD is not fixed a priori (free to vary).
as well as adjusting our fitting algorithm for the modified EMT and for larger WGM spectra.
This is followed by the presentation of a fitting algorithm for real speech data in Estimation method to help estimate the physical parameters.
We developed neural network (NN) inverse models and a fitting algorithm for estimating OPs in two-layer turbid media over the 350-600 nm range.
The ITC data used the kinetically determined Kd value (1.4 nM) as a fixed constant into the fitting algorithm for binding to the first site of the SaMTAN dimer.
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Fitting algorithms for binomial regression and linear risk regression models were stabilized using Poisson residual and robust variance estimation (Greenland [2004]; Spiegelman and Hertzmark [2005]; Zou [2004]).
On the other hand, an accurate curve fitting algorithm is not resource-effective for embedded platforms.
For the sigmoid model we use the model fitting algorithm proposed by [ 31], which is implemented in the Gist package.
These methods have special subroutines for getting output for user-defined time points, which is essential for fitting algorithms.
Cytokines and chemokines were quantified using a Human Lincoplex 30-plex bead array kit (Linco, St. Charles, MO) modified from the manufacturer's instructions to provide higher statistical power for curve fitting algorithms by applying a nine-point standard curve rather than the recommended six-point standard curve (see Table 2 for a complete list of the thirty cytokines and chemokines analyzed).
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