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These model fits project that the intervention averted 624 (Uncertainty range: 310 1,191) HIV infections amongst CSWs in Ahmedabad from the beginning of September 1999 to the end of November 2003 (51 months) – 53.8% (Uncertainty range: 38.4%–68.8%) of the HIV infections that would have occurred without the intervention.
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That's the idea behind Kyle McDonald and Lisa Kori Chung's Open Fit project.
In this article, we aim to outline the intervention and research design of the PRO-FIT project.
Results of the PRO-FIT project will provide information about the effects and implementation of a healthy lifestyle intervention for individuals with FH.
The ethical principles of the Helsinki Declaration were followed and the PRO-FIT project was approved by the Medical Ethics Committee of the VU University Medical Centre (reference number: NL23932.029.08).
In 2009, we started the PRO-FIT project (PROmoting a healthy lifestyle in people with Familial Hypercholesterolemia (FH) through an Individually Tailored lifestyle intervention) [ 7].
The intervention of the PRO-FIT project was developed according to the integrated model for exploring motivational and behavioural change, the I-Change model (2.0)[ 20].
The purpose of the PRO-FIT project was to reduce cardiovascular disease (CVD) risk by promoting a healthy lifestyle in people with FH.
During the PRO-FIT project, five participants in the intervention group dropped out (i.e. their participation was discontinued with a given reason).
Despite its representativeness, only 34% of the people with FH invited to participate in the PRO-FIT project took part in the study.
During the six months of recruitment for the PRO-FIT project, nearly 6200 people in the Netherlands were screened by StOEH, of whom an averaged 35% actually did have FH [ 42].
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