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Determination of fitness function and calculation of individual fitness: This model aims at the shortest total travel time in certain zone.
Considering a global advantage of being a slow acetylator (and a roughly equivalent effect of all slow-causing mutations on phenotype and fitness), this model assumes that the different slow variants of NAT2 may have simultaneously become targets of directional selection, thereby generating an excess of intermediate-frequency haplotypes.
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The fitness of this model was well demonstrated by dead-end filtration test, and its general applicability was validated by the filtration performances under varied filtration conditions and using different filter materials.
It should be emphasized that fitness in this model only refers to replication rate.
The simple fitness definition in this model is actually as favorable as possible to HGT.
Like individual selection models with multiplicative fitnesses, selection in this model does not generate linkage disequilibrium between the competition and policing loci.
Why isn't this fitness model, who obviously got her fitness model body by lifting heavy, showing heavy lifts?
This model fitness was assessed by the Hosmer and Lemeshow goodness-of-fit test.
The fitness landscape resulting from this model is called the "n-k landscape".
Because of mutations, the population spreads out along the fitness axis, which in this model is equivalent to the number of deleterious mutations in a genome.
On the GMAKr model, DE with F = 0.8, λ = 0.5, and CR = 0.3, and a population size of 100 gives the best median fitness of 20.369 for this model.
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