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Competition assays were used as a more stringent measure of fitness differences in mutants with different codon pair biases.
However, is it important to identify alleles with very small fitness differences?
Our model incorporates drug properties, fitness differences between susceptible and resistant strains, mutation, and adherence.
FD-BBO is obtained by incorporating the concept of fitness differences in original BBO.
Objective: We sought to assess reproductive fitness differences between mitochondrial deoxyribonucleic acid haplogroups at high altitude.
Moreover, the 2 isolates exhibited clear fitness differences in competitive growth assays.
In my view this type of study is more important than the identification of alleles with minor fitness differences.
Integrating generalist pathogens with broader coexistence theory, the model measures the pathogen's effect on host niche differences and fitness differences, which determine the outcome of competition.
Niche and fitness differences control the outcome of competition, but determining their relative importance in invaded communities-which may be far from equilibrium-remains a pressing concern.
This way requires that there are ecological fitness differences, and that we can detect them.
At low-nutrient levels, fitness differences between wild type and the constitutive mutants were unchanged or reduced (especially in cpr5).
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