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We further explore this space for a set of parameters whose fitness dynamics was close to the one observed, and the parameter values of s = 0.16, U = 1.5 showed a good fit with the observed fitness dynamics, where both the rates of mean fitness decrease are not significantly different.
Viruses are unable to replicate without infecting host cells, a process which commonly leads to host fitness decrease [1], [2].
This is due to the fitness decrease of all variants especially the wild type in the presence of AZT and the respective reduction of the difference of their products (see equation 1 and figure 2).
Alternating replication in vertebrate and arthropod organisms would impose contrasting selective forces, where fitness increase in a given host cell type leads to fitness decrease in the other, generating a scenario of viral sub-optimal adaptation in each host milieu.
Although outbreeding depression (i.e., the fitness decrease caused by breeding genetically distant individuals) should also be considered, it is clear that in a population affected by inbreeding depression by drift a new immigrant has increased opportunities to contribute to the gene pool.
Furthermore, also the strong apparent fitness decrease during the two matches before the coach dismissal is significantly more pronounced for ΔG as compared to P. This is partly due to the fact that points are (trivially) bounded from below whereas no such bound exists for ΔG.
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For instance, acute spikes in training load increase injury risk, however, greater aerobic fitness decreases susceptibility (Malone et al. 2016).
According to Table 1 and Fig. 6, one can deduce that the processing requirement has increased with channel increase, and then the optimal fitness decreases.
"Astronauts' bones become weaker and their physical fitness decreases the longer they spend in space, much like an elderly person leading a sedentary lifestyle," says Dr Green.
As phenotypic values depart from the origin, fitness decreases.
As mutational load increases, the relative fitness decreases through reduced reproductive rate or reduced survivorship [14], [15].
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