Sentence examples for fissure closure from inspiring English sources

Where does SALL2 fit within the molecular pathways important for fissure closure?

SALL2 is expressed in the developing human retina at the time of, and subsequent to, optic fissure closure.

Our analysis suggested that SALL2 plays a specific role in optic fissure closure required independently of PAX2.

A failure to complete this movement might have implications for chorioretinal coloboma, which is characterized by faulty choroid fissure closure.

Neural tube closure involves fusion of the neural plate, and bears similarity to the process of optic fissure closure.

These data support a role for SALL2 during human eye development prior to, and maintained during and after, optic fissure closure.

Interestingly, a JNK1/2>BMP4/SHH>PAX2 signaling pathway is implicated in both optic fissure and neural tube closure defects (39).

Although P. alecto does have vision-related enrichments given the presence of "closure of optic fissure" (P = 0.00026) "positive regulation of lens epithelial cell proliferation" (P = 0.00026), and "regulation of lens epithelial cell proliferation" (P = 0.00026), these were all based on the ranked position of a single gene, SOX11.

The induction of the eye field is followed subsequentially by a formation of optic cup through invagination of optical vesicles, change of the optic stalk to optic nerve and retina, and by the closure of choroid fissure (Gestri et al. 2012).

Among various phenotypes in Bst+/− mice, the most interesting are its retinal abnormalities, consisting of delayed closure of choroid fissures, decreased ganglion cells and subretinal vascularization.

This defect, coloboma, results from incomplete closure of the optic fissure during development [30].