In post-mortem brains from individuals with Alzheimer's disease, changes in the fusion and fission protein levels by transcriptional regulation of Drp1, Fis1, Opa1, Mfn1 and Mfn2 have been observed [ 253, 254].
To maintain safety margins later in life, some design or operating restrictions can be defined, for example to compensate higher fission gas release levels.
In fission yeast, reduced carbon levels (that reduce cellular energy levels) and changes in amino acid concentrations are both actively sensed [ 17 19].
Fusion power stations inherently will have no actinides or fission products, extremely low levels of nuclear energy, and low levels of decay heat power.
As for HTR-10, the coupled models, TRIFA and DIFA, are applied to calculate the level of fission product release after accidents.
Although the load withstanding capability of the containment structure has been assessed to be substantially higher than the design pressure of the structure (typically 2 times of design pressure), but, it is possible that a few components of Containment System may degrade leading to excessive release of radioactive fission gases at ground level.
They also demonstrated that pre-ischemic hyperglycemia could increase the level of fission proteins DRP1 and Fis1 (Kumari et al., 2012).
In fission yeast, the intracellular level of cAMP is kept high during cell growth and division.
Thus, cardiomyocyte-specific in vivo inhibition of mitochondrial fission has revealed another level of crosstalk between mitochondrial dynamism and quality control.
Shah, S., Wittmann, S., Kilchert, C. & Vasiljeva, L. lncRNA recruits RNAi and the exosome to dynamically regulate pho1 expression in response to phosphate levels in fission yeast.
