Sentence examples for fission factor from inspiring English sources

Mitochondrial fission factor.

In addition, AMPK could directly regulate mitochondria biology through phosphorylation of mitochondrial fission factor (MFF) (Toyama et al., 2016).

We focused on two candidates, cingulin and mitochondrial fission factor (MFF), and further characterised/validated them as AMPK-dependent targets by immunoblotting with phosphorylation site-specific antibodies.

Another class of GTPase proteins including dynamin-related protein 1 (Drpromotemitochondrialdrial fission by interacting with its adaptor in the outer membrane such as fission protein 1 (Fis1) and mitochondrial fission factor [5]. Imbalanced mitochondrial dynamics are directly linked to many human diseases including neurodegenerative diseases, metabolic disorders, and cancer [6].

And, the optimization objectives for the reactor core are, high breeding of U-233 and Pu-239 in desired power peaking limits, desired effective and infinite neutron multiplication factors, high fast fission factor, high thermal efficiency in the conversion from thermal energy to electrical energy using the Brayton cycle, and high fuel burn-up.

Four central nuclear engineering parameters describe the neutron lifecycle: the reproduction factor η, the thermal utilization f, the resonance escape probability ℘, and the fast fission factor ε. The product of these four factors is utilized to compute k∞ of a thermal reactor, whereas the fast reactor k∞ can be expressed with a subset of these four parameters.

However, the relatively loose mitochondrial clusters and extremely restrained staining patterns at the mitochondrial contact site suggested that the mechanism of the fusion phenotype induced by overexpressing Mfn2 was distinctive from that of fission factors.

Here, we investigated the impact of mutations in endogenous PINK1 and Parkin on the ubiquitination of mitochondrial fusion and fission factors and the mitochondrial network structure.

Based in particular on studies with S. cerevisiae we now know that mitochondrial fusion and fission factors can become modified with Ub or Ub-like proteins [5] [8].

Furthermore various proteins involved in mitochondrial dynamics belong to the group of TA proteins (Table 1) including the mitochondrial fission factors Fis1 [9] and Mff [10], and the proapoptotic protein Bak which also regulates mitochondrial morphology in non-apoptotic conditions [11].

In our present work, we used fibroblast cultures from PD patients carrying two mutated Parkin or PINK1 alleles to investigate the consequences of mutations in endogenous PINK1 and Parkin on the ubiquitination of mitochondrial fusion and fission factors.