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Comparison of recovery rate of the caudal fin, measured every two or three days from one day post amputation until 13 days post amputation, show that fins in young and old fish regenerate at a similar rate.
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ARF GFP transgenic fish regenerated their fins normally.
Young fish regenerated more rapidly and almost completely restored their original fin size in comparison with older fish.
The induction and stabilization of p53 and induction of cdkn1a transcripts by ARF showed that ARF impacts p53 functions in vivo in fish regenerates.
Whereas regeneration in humans is limited, several vertebrates, such as salamanders and fish, can regenerate amputated body parts with high efficiency (reviewed in Stoick-Cooper et al., 2007).
Many species, notably amphibians and certain fish, can regenerate a wide variety of their body parts.
An adult zebra fish can regenerate a damaged heart with no scar formation.
Animals like newts and zebra fish can regenerate limbs, fins, even part of the heart.
Many little animals, like newts and zebra fish, do regenerate parts of their bodies.
Zebra fish can regenerate the tip of the heart when it is cut off.
"Birds and fish can regenerate their hair cells, and we've done it on frogs," said Dr. John House, president of the House Ear Institute, a nonprofit research group in Los Angeles, which is working on hair-cell regeneration.
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