This single substitution Q10Y was firstly reported responsible for improvement of the thermal tolerance of α-glucosidase, and may help for guiding molecular engineering of other α-glucosidases for thermostability improvement.
Firstly, those responsible for the allocation of scarce healthcare resources in any country must carefully evaluate whether the efficacy evidence of expensive technologies such as ICD therapy apply to their use outside of clinical trials.
Firstly, it is responsible for the creation of genetic variability during meiosis by directing the formation of reciprocal crossovers that result in random combinations of alleles and traits.
Firstly, they are responsible for overseeing the strategic direction of health service delivery, and hence, they play a critical role in the implementation of any health sector reforms (6, 8).
Firstly, the responsibility for caring, outside state-organised schemes, often falls to women – and usually to the middle-aged mother who is also still mainly responsible for bringing up children.
Firstly, country teams were responsible for research within their own countries, where their knowledge of the context could be utilised to its fullest potential.
"Firstly, the stock response that these are isolated cases, and bad apples are responsible, will not wash with voters if there are new elections.
The FRO2 [ 4] and IRT1 [ 5] were firstly cloned from Arabidopsis and responsible for these processes.
In order to study the genetic architecture of growth traits, we firstly identified genes that are responsible for growth traits.
Firstly, we mapped the domain of CLU responsible for the interaction with HSP60 by pull-down and western blot assay with a HSP60 antibody.
