Sentence examples for firstly altered from inspiring English sources

Firstly, altered epigenetic marking of specific genes resulting from chronic stress may have been transmitted directly to the offspring.

Firstly, it altered collagen metabolism by increasing uPA-mediated proteolytic processing of TGF β in muscle fibroblasts.

Firstly, protein-altering variants, copy number variations and structural variations show consistency with the expression level of genes in the RNA-seq data.

Feedback should be used firstly to alter initial unwanted behaviour and this should ideally move into desired behaviour as an intrinsic driven and well-conditioned behaviour.

Firstly, SFAs might alter the synthesis of phospholipids, which are known to regulate signaling events.

17 Firstly, polypharmacy can alter absorption.

Firstly, phosphorylation alters the disposition of the central membrane-anchoring α-helix with respect to the membrane which could modify how the proline-rich region is presented to the cytoplasm for binding; and secondly, the formation of salt-bridges involving the phosphorylated threonines and basic residues within the proline-rich region could reduce its flexibility [ 23].

Firstly, epidermal cells had sometimes different or altered size proportions (Fig. 5J,L N).

Firstly, the abundance of D1R, their specific activity, and subcellular localization are altered in renal tubules of PAN-NS rats.

Firstly, one-third of miRNAs robustly expressed in muscle (62 out of 171) have altered expression in diabetes patients and a subset of these is altered early in disease where patients remain untreated.

Firstly, the masses combine and secondly, the structure of at least one binding partner is altered, mechanically transducing the binding into subsequent biological reactions.