Mike Owen of the Medical Research Council's Centre for Neuropsychiatric Genetics and Genomics, said: "This degree of convergence from several studies is unprecedented in schizophrenia genetics and tells us that for the first time we have a handle on one of the core brain processes that is disrupted in the disorder".
"This is the first time we may have a handle on how long memories last," says neurobiologist Fernando Nottebohm, the study's head author.
The team's work "is the first time we're getting a handle on how signals outside the growth cone control the cytoskeleton," says neurobiologist Shelley Halpain of the Scripps Research Institute in San Diego.
But having broken the code, "We think that for the first time we have a real quantitative handle" on exploring how the nucleosomes and other proteins interact to control the DNA, he said.
"I think for the first time we're starting to get a handle on this," said Pound, who is chairman of the World Anti-Doping Agency, which the I.O.C. created.
The first time he handled the ball, he tried to drive into the lane and was whistled for a charging foul.
Morgenstern won the Four Hills tournament, staged in Austria and Germany, for the first time, then handled the pressure to take three gold medals and a silver on the rebuilt Holmenkollen jump at the world championships in Oslo.
Hot Blade, a heated windshield-wiper system recently patented by an inventor in North Dakota, is being produced and distributed this winter for the first time; it is handled by Rostra Precision Controls Inc., an automotive supplier in Laurinburg, N.C.
The shots in the trailer showcase Anderson's set design and eye for composition which should be in full effect on Phantom Thread since the film will be the first time the director handled cinematography duties himself, as well.
The first time you handle an older coin, just stop for a minute and let your imagination soar.
