Sentence examples for first time proof of from inspiring English sources

This phase I study had a pharmacodynamic endpoint of PARP inhibition in PBMCs, demonstrating for the first time proof of mechanism of the class.

In this study, we developed an in vitro model showing for the first time proof of and the mechanism for a soft-tissue component of ONJ, whereby after release from bone, BP induces gingival fibroblast and epithelial cell death via apoptosis, with the continued release of ZA preventing spontaneous resolution or healing, due to inhibition of cell proliferation.

We also provide a first-time proof-of-concept of biplex detection of VC and Escherichia coli (EC) targets in the portable AC susceptometer.

Concluding, for the first time proof is given that viral agents at least of the myxovirus family - here influenza A/H1N1 - can induce pure often fatal AFOP.

Herein, we describe for the first time the proof-of-concept of CXCR4-directed PET MRI with [68Ga]Pentixafor in response assessment in a patient with extranodal marginal zone lymphoma (MZL) of the orbital cavities and compare it to standard [18F]FDG PET imaging.

He was the first Austrian margrave to describe himself as the holder of territorial principality (principatus terrae), and during his time Austrian common law was mentioned for the first time, another proof of the developing national consciousness.

9– 11 Here we provide, for the first time, an experimental proof-of-principle of such a phase-change material-based "processor".

The song about hearing "Like a Rolling Stone" for the first time was proof enough of that.

In conclusion, we here for the first time in a proof-of-principle model demonstrate that residual therapy-resistant cancer cells can be killed when the resistance is due to PI-9 expression as escape mechanism.

In a landmark ruling last year, the judge in an appeal by Louise Barton, a media analyst with Investec, another City investment firm, clarified for the first time new burden-of-proof regulations, introduced in 2001.

This model system, for the first time, provides the "proof of principle" that increasing vessel density at the sites of implantation can enhance glucose sensor function in vivo, and demonstrates the potential of gene transfer and tissue interactive fibrin bio-hydrogels in the development of successful implants.