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Therefore our work links for the first time progression of the cell cycle to progression of spindle morphogenesis via the accumulation of a cytoskeleton component, TPX2.
In summary, we have presented for the first time progression rates to i-IFG, i-IGT, and IFG-IGT in a large European population-based study, which uses the current WHO classification criteria.
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To demonstrate that suppression of inflammation and its consequent CNS tissue damage contributed to the neuroprotective effect that was observed in the present experiments, we studied here for the first time the progression of the inflammatory process and the tissue damage in a time course experiment.
Our work identifies for the first time atherosclerosis progression-specific DNA methylation profiles in the vascular tissue.
In conclusion, this study shows for the first time that disease progression can be assessed by measuring lung function over time in the same animal.
It is for these reasons that in the present investigation we first followed the time progression of IVD degeneration in Bgn−/0 mice by high resolution MRI, and then processed discs for histological analyses.
Progression-free survival was similarly determined as the time from pathologic confirmation of the surgical specimen, prior to therapy, to the first time of disease progression, as evidenced by a persistent 20-point decrease in Karnofsky functional status and available clinical and/or radiographic data.
Our outcomes included first clinical decompensation event (evaluated for the first time), HVPG and fibrosis progression defined by CPA and Ishak stage.
This demonstrates for the first time that lung cancer progression relies on tumour-associated macrophage-lineage cells not only at advanced stages but also at pre-malignant stages.
Nor is this progression the first time that a lavish commitment to finance the college education of strangers has started a trend.
We report for the first time that suppressed breast cancer progression and metastasis in mice lacking ST2 corresponds mainly with enhanced cytotoxic activity of NK cells, and increased systemic Th1/Th17 cytokines.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com