The first time CGRP was hypothesized to be involved in migraine was in 1985 [1].
The doctoral work of Shankar Chellam demonstrated for the first time that our hypothesized minimum in particle transport from membrane surfaces is indeed observed and leads to preferential accumulation of particles of an intermediate size on the membrane.
We demonstrate and directly observe for the first time what has only been hypothesized, that osk is transported and anchored in large, higher order RNP assemblies that are constantly reshaped in their form during transport.
For example, in therapy-naïve children receiving MPH for the first time, two subgroups might be hypothesized to exist: responders, showing good symptom reduction over time, and partial responders, who show few or no treatment effects.
With regard to the final item, we might hypothesize that first time transplant recipients may be more clinically urgent or more likely to have an undiagnosed immuno-incompatability than repeat transplant patients.
Since we observed these cells in the subepicardium of 13 dpc mouse hearts, we can hypothesize for the first time on the existence of hematopoietic potential in the subepicardial cells.
TMZ also posted several photos of Jackson with scars on her wrists, hypothesizing that this incident might not be the first time that Jackson cut her wrists.
We hypothesize that amongst women experiencing GBV for the first time (group 2), there will be a high incidence of first onset mental disturbance within one and five years following exposure.
We studied for the first time the oxidative nature of CeO2 nanoparticles (NPs) on in vitro systems and we hypothesized that if the oxido-reductive behavior of Ce is not well utilized which may lead to adverse toxic effects.
Although reasons for the delay remain unknown, we hypothesize that WNV activity in Washington State in 2009 provided, for the first time, a sufficient nearby source of WNV for northward introduction of the virus into British Columbia through cross-border mountain valleys.
