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Here, we established for the first time a functional link between cystatin C and MAPK-Erk signalling and AR-mediated pathways in prostate cancer cells.
Our study shows for the first time a functional link between WIF1 and miR-200c, and reveals a novel mechanism by which WIF1 could suppress salivary gland tumor progression.
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Our study reveals for the first time a functional connection between BET proteins and SIRT1.
These data for the first time demonstrate a functional link between calpain activation, vimentin cleavage, vimentin reorganization, and membrane translocation of MT1-MMP in EC sprout initiation.
Therefore, this will be the first time a direct functional link between Akt and Bmi-1 is made.
Nevertheless, these results demonstrate for the first time a plausible functional link between menopausal genetic variants and oocyte number in women of European ancestry.
A first evidence of a functional link between TRIM32 and malin was found in the ubiquitination of R5/PTG: we observed that TRIM32 is able to ubiquitinate this substrate.
The study shown for the first time the existence of a functional link between sIL-1Ra and mutp53, adding further insights for the identification of novel non-cell-autonomous GOFs mutp53 in human cancer.
Our results demonstrate for the first time a functional relationship between EVI1 and miRNAs expression.
In general, high first-order similarity suggests the existence of a functional link between two genes, and clustering based on the second-order similarity captures multiple functional links always activated and deactivated under similar conditions.
To establish a functional link between these processes, we first examined the possible activation of MAPK and CDPK in cells irradiated with UV-B.
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