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Alternatively, lysosomal membrane proteins are first targeted to the plasma membrane for subsequent endocytosis.
According to our results, newly synthesized HN is first targeted to binding to receptors.
These results suggest that ABCB6 is first targeted to the plasma membrane to be internalized by endocytosis.
PM proteins, lysosome proteins and secretory proteins are first targeted to ER and then to the Golgi apparatus for modifications before being transported elsewhere.
Thus, plastid proteins are first targeted to the outer membrane via a hydrophobic signal sequence and secondary targeting signals mediate uptake into plastids [ 47].
In vivo pulse-chase experiments using Pex3-GFP in S. cerevisiae pex3 cells (Hoepfner et al. 2005) revealed that Pex3-GFP is first targeted to the ER, but later present in new, small peroxisomes.
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Second, targeting to the MOM is dependent on a short TMD [5].
"We have reached our first target: to go through into the knockout," Conte said.
His aides said they expected the first targets to be the massive infrastructure projects that were the hallmark of the former administration.
So, the revenue of PU described in (1) is our first target to solve.
Without him for the rest of the first innings, England have to knuckle down and show great fight, with their first target to beat the follow-on.
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