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The first suggestion that BAG3 could play a role in adult-onset familial dilated cardiomyopathy came from a study of patients with a dilated cardiomyopathy, diffuse myocardial fibrosis and sudden death.
The first suggestions of a possible Twist1 dysregulation came from genetic studies performed by Davis et al. showing that the NF-κB pathway was constitutively activated in activated B-cell-like and primary mediastinal B cell-like DLBCL.
Interestingly, this is not the first suggestion that a Ly6 family member interacts with αVβ3 integrin.
The first suggestion that CDX2 autoregulation could be relevant in vivo came from heterozygous Cdx2 null mice.
This is the first suggestion that the -271 G>A polymorphism of the KDR gene may be functionally associated with the regulation of the gene's transcription level.
The first suggestions that football might be involved came 24 hours before the opening match in the capital Brasilia.
The discrepancy between these results and the first suggestions of Erayman et al. [ 12] that most of the genes are located in the distal parts of the wheat chromosomes may originate from their use of a consensus deletion bin map from the A, B and D chromosomes, where markers were non-systematically assigned to the deletion bins [ 51].
These sites, and 23 others, are Google's first suggestions for each letter of the alphabet.
The first suggestion that CBP and p300 may regulate growth and function as tumour suppressors was provided by studies of adenovirus E1A's transforming properties.
Furthermore, this is the first suggestion that Nor-1 regulates effector CD8+ T cell fate.
For instance, if I set out to find out if 9/11 justified the War in Afghanistan, the first suggestion questions whether 9/11 happened at all.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com