Next, we determined whether deacetylation, the first step of activity-based HDAC detection by HP-1, could be effected by recombinant HDAC enzymes.
This first step of the activity is equivalent to the genetic drift process; however, at this point it is only intended as an aid for students to be able to formulate hypothesis and explanations for the second step of the activity that focus directly on natural selection.
Since the ICBM's entrance onto the world stage, Pyongyang has continued to up the ante, firing an intermediate-range missile over northern Japan in a move the United Nations Security Council blasted as "outrageous" and Pyongyang called "just the first step" of heightened military activity in the Pacific. .
The evaluation of the accuracy of the component approach for predicting the rotational behaviour of base plate connections up to failure under monotonic loads has been carried out as first step of the planned research activity.
As a first step of reevaluation the aEEG background activity was evaluated by a single expert reader (Anna Csekő) who was blinded to clinical history and symptoms of encephalopathy.
SDS was added to tissue homogenates at the very first step of sample processing to arrest enzymatic activity and minimize unwanted loss of PTMs.
Depletion or repression of APC/C activity prevents the first step of securin destruction and results in a metaphase arrest.
Results obtained in the first step of the study indicate a notable antibacterial activity of bioglass BAG-S53P4 granules at two different concentrations (800 mg/mL and 400 mg/mL) against methicillin resistant S. aureus and S. epidermidis, and multiresistant P. aeruginosa and A. baumannii.
The first step of the analyses identified PFC voxels exhibiting differential activity during (M+) vs. (R+) trials.
The peptide-membrane contact is the first step of the sequential processes leading to peptide internalization and cell activity.
The first step of this kind of investigations is in vitro analyses, e.g., mitochondrial activity.
