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The DYX2 locus was first refined by high dense SNPs (~21 kp apart) and showed a significantly associated region that contains five genes: VMP, DCDC2, KIAA0319, TTRAP and THEM2[ 5].

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In brief, we first refined the molecule by performing an optimized geometry calculation saved in Protein Data Bank (PDB) files using the conversion filters in CAChe software (v 6.1) (Fujitsu America Inc., Beaverton, OR, USA).

To define the physical association of ScUrn1 with ScPrp19, we first refined the interaction domains by directed two-hybrid analysis.

To obtain the 3D reconstruction of the SWR1-nucleosome complex, we first refined our apo-SWR1 model, obtained by refining the OTR model against 2D class averages of apo-SWR1, against 2D class averages generated from the SWR1-nucleosome data.

By studying mouse and zebrafish RP promoters bioinformatically we first refined the definition of the LTSM sequence motif.

Petrol was first refined in a building on Hepscott Road, E9.

The search strategy was written by the first author and refined by a medical librarian (CB) and an experienced systematic reviewer (MB).

With its endless repetitions of a sweeping theme, the work made the Rachmaninoff Second Concerto sound refined by comparison.

"First, refine your interest," she said.

The idea was conceived by the first author and was inspired and refined by the second author.

Like the previous relaxation of policy in 2013, this policy change must first be endorsed and refined by the central government and then implemented by provincial-level governments, which can introduce their own variations on the general policy.

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