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In addition to xenobiotic metabolizing enzymes involved in the first phase of detoxification, we also identified genes involved in the second phase of the xenobiotic metabolism, particularly glutathione-S-transferase (GST), which was over-expressed by 1.5 fold in the heavily-polluted Tiber site.
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Glutathione S-transferases (EC 2.5.1.18; GSTs), also known as glutathione transferases (GTs), are involved in the second phase of detoxification processes.
First phase of the beginning".
The first phase of the execution is completed, we are now into the second phase.
Denial: the first phase of grief.
The Crisis Phase The first phase of affair recovery, the crisis phase, happens when an affair is disclosed or discovered.
Phase I enzymes are involved in the first stage of detoxification of xenobiotics compounds and implicates in enzymatic transformation of a chemically modifying lipid soluble toxin into water-soluble toxin.
A second phase of construction is planned.
II) The second phase of the first algorithm (Phase II).
Furthermore therapeutic recommendations for the acute phase of detoxification vary considerably between studies [1, 2, 17 19].
As a consequence, the therapeutic strategies for the acute phase of detoxification and the use of preventive treatment differ widely between studies [8].
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