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Kinematic analysis based on polyhedral modelling can be used for first pass analysis but cannot capture composite failure mechanisms involving both structurally controlled and rock mass progressive failures.
There were 484 nominal polymorphic sites, and in this first pass analysis, all SNPs were calculated for association, without regard to haplogroup specificity or minor allele frequency.
As a first pass analysis, we plotted the MS/MS ion intensity at m/z-98 for all obtained precursor m/z values, using the "Ion Map" function of the Xcalibur Qual Browser program (Thermo-Finnigan).
Since the original assignment of samples to tiers was not readily available, we did a first pass analysis of the entire data set – without attempting to reduce to the cleanest samples – using the same parameters as we used on the TCGA data set.
Additional candidates may be identified with publication of new miRNA expression studies in NSCLC as half of the miRNAs with concordant copy number changes (10/18) were excluded from this first pass analysis as their mature expression levels have not been measured.
Consequently, MALDI-TOF-MS was the first pass analysis.
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In the first-pass analysis we identified sample groups with significant changes in the status of each module.
Samples harboring DNA variants were re-sequenced at least once using an independent DNA aliquot from the first-pass analysis.
From the First-Pass Analysis, we were able to generate preliminary brucellosis information that enabled us establish custom terms (values) for describing disease parameters (Supplementary File S1).
Profiling tumours with RTK capture arrays may be very helpful in first-pass analysis of tumours to identify active RTKs that may be susceptible to treatment with the kinase inhibitors.
It provides a listing and a first-pass analysis of the expression of all 662 genes; it compares the expression patterns of glycolytic and TCA cycle genes; and it compares the expression patterns of 15 of the 16 known CAs in order to illustrate the astonishing diversity of expression patterns exhibited by members of a single multigene family.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com