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end{array} (13) Fig. 2 First order prediction.
The chance that a random guess of a protein phenotype will succeed is 1.7/11 = 15.4%, much lower than the first order prediction success rate.
As a result, the first order prediction accuracy of our method achieved 65.4% evaluated by Jackknife test of 1,267 proteins in budding yeast, much higher than the success rate (15.4%) of a random guess.
There are 24 protein functional categories, meaning that in average a random guess of a protein function will have a success chance of 13.1% ( <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0014556.e172.PNG" class= inline-graphic"/> ), much lower than the first order prediction accuracy of 69.1%.
In view of this, the first order prediction accuracy is the most important indicator of the performance of the method.
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First order predictions are of sensory input, and therefore drive (or inhibit) prediction error units in the level below, as we described in the first section.
This allows us to rapidly test first order predictions that efficient circle production relies on the presence of a trans-acting factor binding site.
Second, this could also be the case for the 'slow' CM neurons in M1 (the majority), as predictions of precision are slower than first order predictions, as outlined above.
Last, we would argue that most of the CM system allows the specification of fine-grained, fractionated patterns of motor gain (as well as its first order predictions), in contrast to the diffuse descending neuromodulation found in other systems (Heckman et al. 2008).
Here, we treat the contact of the particles as follows: the time and position of the contact to a solid surface of the particles in nodal points (in the finite element discretization) was calculated with an explicit second order prediction.
Thus such second order predictions significantly raise the sensitivity of 3D template annotations for structural genomics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com