Sentence examples for first of all require from inspiring English sources

Investigations following stroke first of all require information about the spatio-temporal dimension of the ischemic core as well as of perilesional and remote affected tissue.

This will first of all require a better understanding of factors that are at play in the decision-making of parents and children to continue schooling until completion or to abandon schooling.

A modern chemical industry first of all requires an economical chemical production.

As Dr. Lipscomb said: "For me, the creative process, first of all, requires a good nine hours of sleep a night.

However, since species vary in the extent of their geographical ranges, variation among ethnobiological systems will reflect not only cultural but also biological diversity, since nomenclatural recognition first of all requires that a species exist locally.

The Dutch scientific community realized that nanotechnology first of all requires state-of-the-art facilities.

The application of this method first of all requires the construction of two more sectors (T_{j}^{3}) and (T_{j}^{4}), where (0< r_{j4}

Since the largest proportion of the economic rent in these GVCs is created in the R&D and marketing segments, making adequate use of the windows of opportunity first of all requires to have the right kind of personnel and pursue appropriate education, S&T, and innovation policies.

In order to promote this regime, it is first of all required to increase the doping concentration (N D), ideally to values above the metal-insulator transition (MIT) concentration (for our design, typical concentration used is N D ≈ 1 × 1019 cm−3) [19].

We would like to agree with Hermanek (1999), who proposed that the introduction of an advanced examination of lymph nodes regarding isolated or disseminated tumour cells first of all requires standardization of the procedure and description of the clinical relevance.

Not withstanding the inhibitory role of TIMP-2 on MMPs activity and its MMP-independent inhibitory role in angiogenesis, TIMP-2 is first of all required in stechiometric amounts for MMP-2 activation by MT1-MMP [ 31].