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First, neutralization aimed at cell binding may be cell type-specific.
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Second, neutralization often reflects reduced rather than ablated infectivity.
Two of the three antibodies, QA255.087 and QA255.187, demonstrated modest cross-clade neutralization (IC50 1.6–10.8 μg/mL) against a second neutralization-sensitive clade B variant SF162 (Table S2).
A first serum neutralization assay resulted in titers of ≈15 for serum collected 21 dpi.
We first tested the neutralization activities against HA pseudoviruses derived from the contemporary human seasonal influenza A viruses, including BR07 H1 and MO99 H3.
Although J774 cell treatment with zVAD.fmk induced necroptosis, cell death was not dependent on the production of TNF α. Cell death was observed beginning at least 12 h after the increase in TNF α was first detected and neutralization of TNF α was not sufficient to block zVAD.fmk-induced necroptosis of J774 cells.
Second, to examine neutralization activity, 50 μl of HCV-infected serum were pre-incubated with the purified proteins in 1 ml media at 4°C for 60 min.
The first reaction is a neutralization, the second one is the Dushman reaction between the iodide and iodate.
The iron (II, III) oxide (Fe3O4), magnetite core is first prepared by ammonia neutralization of ferrous and ferric chloride aqueous solution under argon, followed by the addition of citrate salt to stabilize the surface of the resultant magnetic nanospheres.
First, we employed a neutralization strategy to analyze the contribution of IL-17A and/or IL-17F in S. Typhimurium enterocolitis.
Recombinant ASP (rASP) activation and antibody neutralization were first tested in an in vitro system.
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