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The standard assessment of GTT patients includes the FIGO prognostic score, which is based on a number of key clinical parameters and allows an estimate of the likely first-line cure rate with the low-intensity single-agent drug treatment.
It's lugubrious, lo-fi and low-rent, but it feels kind of literate, too – the first line of the Cure-ish Bad Day goes, "I hope that the last page of your 800-page novel is missing" while on DNA Deez announces that he is down to his "last six or seven chromosomes".
However, azithromycin as first line treatment without test of cure for M. genitalium and subsequent Moxifloxacin treatment of macrolide resistant strains will select and increase the macrolide resistant strains in the population.
The impact of the cell of origin of the lymphoma in terms of response and cure rate to first line and second line chemo therapy treatment has been clearly demonstrated, with overall cure rates in germinal centre DLBCL of approximately 80% compared to only 50% in the activated B cell form [ 170, 171].
First line antibiotics were no longer curing basic infections, and doctors were concerned.
"It's a first line of defence, but not a cure".
"It's a first line of defense, but not a cure".
While short term BV cure rates following first line recommended therapies (5 7 days of metronidazole or clindamycin) approach 80%% [ 38], failure rates in excess of 50%% occur within 6 12 months [ 39, 40].
However, the 6-drug antituberculosis therapy might not be considered as the only reason for cure, since 4 first line drugs showed high-level resistance and chances of cross-resistance between closely-related aminoglycosides, amikacin and kanamycin and quinolones, sparfloxacin and ciprofloxacin could not be ignored [ 21, 22].
I give antibiotics for a diabetic foot ulcer with a first line regimen which has 95percentt certainty of cure.
In the absence of systemic metastases salvage RT could theoretically be assumed to be the first line treatment offering a potential chance of cure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com