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Static and dynamic behavior of a simplified single-edge device was first investigated through the static calibration procedure, pulse tests and preliminary cutting tests.
The influence of process parameters on bulk PEO cross-linking degree was first investigated through a mixture design methodology which revealed that the most influent parameters are extrusion temperature and time.
Differences in cellular Ca2+ homeostasis that might relate to the presence of the P2328S allele were first investigated through changes in the amplitude and pattern of Ca2+ transients in response to regular stimulation (0.5 Hz) in isolated Fluo-3-AM loaded WT (Fig. 2a,b), RyR2 p/s (Fig. 2c,d) and RyR2 s/s (Fig. 2e,f) myocytes.
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We first investigated heterogeneity through visual examination of forest plots of sensitivity and specificity.
In order to characterize the mechanism through which CBD causes apoptosis, we first investigated whether CBD was acting through cannabinoid receptors CB1R or CB2R.
With no prior reports regarding mechanism of cell death of combination SIM+MET in any cancer cell, we first investigated whether cell death is through apoptosis.
The crash behavior of the four types of ATS tubes, namely single-cell straight (SCS), single-cell tapered (SCT), multi-cell straight (MCS) and multi-cell tapered (MCT), are first investigated by nonlinear finite element analysis through LS-DYNA.
As the PAK1 kinase acts on its targets mainly through phosphorylation, we first investigated whether PAK1 might phosphorylate RUFY3.
We first investigated the timing of miR-143/145 gene expression through β-galactosidase staining.
We first investigated modifications to histone H2A and H2A.X-F upon maturation of oocytes to eggs through GVBD.
Police first investigated Sardar in late 2007.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com