Sentence examples for first internalized from inspiring English sources

Dendritic cells have apparently evolved specific cross-presentation mechanisms allowing them to prime CD8+ T cells for exogenous Ags that are first internalized by macro-pinocytosis, phagocytosis, or receptor-mediated endocytosis [31], [51], [52], [53].

Several approaches using elegant methods revealed recently that nuclear FGFRs and FGF1 and FGF2 are first internalized from the cell surface by endocytosis.

This finding suggested that RSV G is involved in a complex recycling mechanism where membrane-bound RSV G is first internalized and subsequently incorporated into viral filaments protruding from the surface.

This was necessary because, as Hegel argued, particularity cannot be the criterion of theoretical or practical reason; rather, individuals must first internalize substance, as a principle of universality, as a stage in reaching infinite self-consciousness.

Jacobs and Angelou both use rape as a metaphor for the suffering of African Americans; Jacobs uses the metaphor to critique slaveholding culture, while Angelou uses it to first internalize, then challenge, twentieth-century racist conceptions of the Black female body (namely, that the Black female is physically unattractive).

As described before, the three lines of cells were either directly stimulated with goat anti-human IgM antibody F ab′ 2 fragments (10  μg/mL) or pretreated with goat anti-human IgM antibody F ab′ 2 fragments (2  μg/mL) at 37°C for 30 min to first internalize cell surface BCRs and then rechallenge them at 2 h or 4 h with goat anti-human IgM antibody F ab′ 2 fragments (10  μg/mL).

First, we internalized E. coli particles and fluorescent baculovirus together for brief periods of time.

Fifth: They internalized the team mottoes we tried to instill in them from the get go.

In a second model, internalized antigens may be delivered to the cytosol where they can follow the classical proteosome-mediated degradation and entry to the ER via TAP for loading on nascent MHC I molecules [8], [9].

In the second step, internalized receptors are sorted through a complex system of intracellular vesicle compartments, known as endosomes [ 39- 41].

In summary, we propose that the BoNT/A complex can be internalized first through the interactions of the HA-C with epithelial cell receptors, likely surface oligosaccharides, and second through interaction of the BoNT/A holotoxin with its own cell receptors.