Sentence examples for first generation configurations from inspiring English sources
The consequences of introducing additional costimulatory domains into second generation CARs have been directly compared against first generation configurations in subjects with B cell lymphomas who were infused with two autologous CD19-specific CAR-modified therapies.
In the autologous setting, Memorial Sloan Kettering Cancer Center researchers have investigated similar second generation configurations, using gRV and ex-vivo transduction following activation with anti-CD3/28 beads, and included pre-conditioning with cyclophosphamide in some patients (Brentjens et al, 2011, 2013).
The second generation configuration supported longer in vivo persistence and responses in 2/6 subjects with non-Hodgkin lymphoma (Savoldo et al, 2011).
GRIDs technology has developed from first generation, supplier-specific and configuration-specific systems through second generation systems providing metacomputing facilities over various underlying platforms.
This was however an older study that used a different electrode configuration and the first generation Kubicek algorithm [ 26].
The first is completing "first generation" reforms.
We're not even first generation.
"The first generation to grow up exercising".
But these "first generation" biofuels have drawbacks.
The first generation of Cyclops were forgers.
