Sentence examples for first difficulties from inspiring English sources

One of the first difficulties in developing monoclonal antibody therapeutics was the recognition that human anti-mouse antibody (HAMA) response limited the administration of murine antibodies.

After the easiest of first weeks, including an ­opening 6 0, 6 0 victory over Britain's No1, Anne Keothavong, she experienced her first difficulties in the quarter-finals against Anastasia Azarenka of Belarus, though even then there was no apparent suggestion that the pressure was boiling up into something beyond her control.

Some historians see Władysław as a dreamer who could not stick to one policy, and upon running into first difficulties, ditched it and looked for another opportunity.

In his younger time he went over into the low countries, and was a soldier there, and came acquainted with the church at Leyden, and came over into New England, with such of them as at the first set out for the planting of the plantation of New Plimouth, and bare a deep share of their first difficulties, and was always very faithful to their interest.

Time management was one of the first difficulties for clinic physicians.

First, difficulties in planning a multidisciplinary surgery such as IBR, probably delays start of chemotherapy.

The first difficulty is the space.

DR. SOWWAN says the first difficulty was fund-raising.

The first difficulty arises with the design of the TEF.

The first difficulty is raised by what is called the air.

The first difficulty is in deciding the appropriate unit for measuring resources.