Your English writing platform
Discover LudwigExact(6)
Bladder volume at first desire to void significantly increased, but maximum cystometric capacity showed no significant change.
These volumes were chosen as fixed values that approximate the commonly observed filling volumes for first desire to void and maximal capacity in patients with DO (see discussion).
In addition, the concentration of ATP in intravesical fluid has been shown to correlate with urinary urgency as indicated by the volume at first desire to void in patients with OAB [ 21, 22].
Moreover, after the intravesical administration of capsaicin, authors observed a reduction of the first desire to void, bladder capacity and pressure threshold for micturition, and an attenuation of symptoms of hypersensitive LUT disorders.
Furthermore, ATP has been shown to play a role in bladder sensation, with ATP concentration in the intravesical fluid correlating with the first desire to void in patients with both overactive bladder [ 3] and painful bladder [ 11] but not in control patients.
In DO, ATP release at 200 mL was significantly higher in those with low first desire to void (FDV) (≤200 mL) than in those with higher FDV (>200 mL); this may suggest that ATP release at early stretch may play an important role in urgency (early sensation) in DO.
Similar(54)
The third task-related fMRI (C) starts with a high prefilled bladder volume (persistent desire to void) and will be performed in all participants (patients with non-neurogenic LUTS and healthy controls) during visits 2 and 3 (first and second MRI measurements).
In women with normal bladder function, insular activation also becomes stronger at large bladder volumes and strong desire to void [4].
We used the overactive bladder definition of International Continence Society, with urgency (defined as sudden compelling desire to void) as a sufficient criterion for overactive bladder [2].
Prior to scanning, bladder volume and the level of desire to void were measured using abdominal ultrasound and a visual analog scale (VAS, ranging from 0 = no desire to void at all to 10 = strongest urge to void), respectively.
On completion of scanning, all subjects again rated their desire to void using the VAS.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com