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Hence, our test data has been generated by letting a human annotator (not part of the first annotation phase) tag tweets from the originally collected Twitter dataset until sufficiently many tweets had been discovered for each emotion.
The mapping step was done using default settings, whereas a lenient E-value (0.1) and lower annotation cut-off (55) and GO-weight (5) were used in the first annotation step to increase the proportion of annotated transcripts.
The first annotation strategy (AS-base) transfers all GO terms annotated to proteins encoded by known disease genes in UniProtKB to the corresponding OMIM entry.
Furthermore, because several gene names have changed since the first annotation was done, updated names from the latest Affymetrix® annotated library are provided in Additional file 2, together with the old ones.> -wrap-foot>> -wrap-foot> List of 19 identified genes selected on the basis of fold change value and known relevance for neurodegeneration.
The first annotation, on the top of the figure, shows that the stmt attribute contributes to the implementation of the persistence concern.
The first annotation pass segmented the recordings with respect to background sounds (speech, music, noise, or none), channel conditions (studio, telephone, outside, and none), speakers, and speaking modes.
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The second annotation annotated SNPs to genes if they were within a 20 kb distance of the gene(s), also from the start to end of transcription.
The second annotation pass provided speech transcriptions and acoustic events (such as throat, breath, voice, laugh, artic, pause, sound, rustle, or noise).
This second annotation would seem to make more biological sense.
A second annotation step was performed using a different database.
The participant costs of the first and third annotation workshops were funded by the 3P20RR016472-09S2 Delaware INBRE Administrative Supplement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com