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Research in this area, however, has been dominated by the medical sciences and subsequently the majority of direct interventions – and their evaluations – on the internet are first and foremost directed to parents with very specific needs.
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First and foremost, direct inhibition of osteoclast differentiation may be achieved by application of RANKL decoy molecules such as OPG and the soluble fusion protein RANK-Fc [ 52, 59].
But both films are remembered, first and foremost, as movies directed by Clint Eastwood, and not as adaptations of books.
First and foremost it is direct personal human-to-human, eye-to-eye contact.
And enduring required that the brutalities and humiliations had to be countered that were directed, first and foremost, at the defining core of their very being that is, at their foundational notions of themselves as persons and as distinctive, racialized peoples so as to bring about their cross-generational living of social death (Patterson 1982).
Empathy alone is not enough to combat it, because empathy is generally directed first and foremost to the powerful.
Jacobi now further develops this point by arguing that Kant's critical system was explicitly intended from the start to serve the interests of science — where by 'science' Kant meant first and foremost a cognition of the understanding directed at the objects of the senses.
First and foremost, Tinder's defensive rant should have never been directed at the writer, especially publically.
In America, direct democracy applies first and foremost to the selection of president.
First and foremost: Really?
Children first and foremost.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com