Sentence examples for first activating from inspiring English sources

Extrinsic pathway involves interaction of ligands (Fas and TNF-alpha) to their transmembrane receptors [ 64], thus activating caspase-8, which further activates caspase-3 directly [ 65] or by first activating intrinsic pathway followed by activation of caspase-3 [ 66].

However, in bacterial systems, both single A domains as well as A-T domain units, known as initiation modules, can interact with other NRPS proteins and accomplish biosynthesis by first activating and then transfering the activated substrate either to a C domain in the same NRPS or to a C domain in a different NRPS (nonlinear biosynthesis) [ 5].

Mentorships, which officially launched three months ago, are getting a smaller expansion: previously Group administrators had to get involved in first activating the option for mentorships in their Groups, and then to actively match mentors and mentees to each other.

They represent the first activating receptors mediating NK cytotoxicity to be identified and molecularly characterized [3].

Immobilization of human IGF-I and -II (Diagnostic Systems Laboratories) was performed by first activating the surface of the sensor chip with a mixture of EDC/NHS followed by injection of IGF-I or -II (10 µg/ml in 10 mM sodiumacetate, pH 4.75).

Its synthesis was accomplished by first activating biotin 18 with N-hydroxysuccinamide 19, facilitated by N, N′-dicyclohexylcarbodiimide (DCC) to give compound 20.

A transition is thus defined as an event whereby a consequent variable has been triggered (or first activated) by the activity of the precedent.

Mature SUMO is first activated by a heterodimeric activator protein via the formation of a thioester linkage.

To determine whether E6 inhibits activity, p53 was first activated by 5 nM OA, a protein phosphatase 2A (PP2A) inhibitor.

Autophagy is activated before apoptosis, suggesting that autophagy is first activated as a protective mechanism followed by apoptosis activation at longer time when the stress is not relieved.

It was announced in October 2014, and was first activated for the having been activated for the earthquake in Nepal in April 2015.