While membrane anchoring firmly restricts LRP4 to the two-dimensional surface of the muscle fiber and thereby ensures its continued presence in the MuSK/agrin/APP/APLP2 signaling complex, the loss of the transmembrane segment can be partially compensated for by the combined interactions of APP, APLP2, MuSK and agrin with the LRP4 ECD.
The women's march on Versailles was a key moment in the French revolution, but the newly empowered category of "citizen" was restricted firmly to men.
This created an x-shaped cross of material on the back of the animal under which the logger could be firmly placed without restricting the movement of the animal's legs and, since the material allows diffusion of air, without restricting cutaneous gas exchange.
Fostered in the traditions of sturdy evangelical piety and liberal reform, he saw the origin and triumph of these values in the Glorious Revolution (1688 89), which firmly established the supremacy of Parliament and restricted the monarchy to a constitutional status.
Scapular movement is restricted by one of the examiners hands firmly placed on the scapula.
To achieve a positive influence on key performance indicators, organizational approaches to enterprise architecture should not be restricted to purely technical aspects but should instead put the focus firmly on employees.
"We firmly believe that this is a powerful, efficient, scientifically based healthcare intervention that can be used in all settings, from those with very restricted to unrestricted access to healthcare".
I certainly didn't, and I was one of those lied to: knowledge of the mission was restricted to the inmost inner circle, a circle from which, throughout the whole post-Sorensen, pre-Favreau era, speechwriters were firmly excluded.
La Yifan told the ruling elite behind firmly closed doors that it must discard the isolationism of the past and open up an economy in which the flow of money and information is still restricted.
His travel is restricted.
