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After 6 and 12 months the repair tissue was evaluated histologically and showed formation of a cartilaginous tissue and good integration into the surrounding host tissue with firm bonding of the graft to the adjacent cartilage and the underlying subchondral bone.
Preclinical evaluation in the large-animal horse model showed the formation of a hyaline-like cartilage matrix as well as firm bonding of the graft to the adjacent healthy cartilage and to the subchondral bone tissue [ 27].
In Haflinger horses, full-thickness cartilage defects of the fetlock joint were treated with the autologous polymer-based cartilage graft, and formation of a hyaline-like cartilage repair tissue as well as firm bonding of the graft to the adjacent healthy cartilage and to the subchondral bone tissue were evident 1 year after implantation [ 44].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com