fast-firing, dopaminergic neurons (with their need to rapidly restore conditions after repetitive, sequential firing of action potentials) or #2. the developing mnd2 mouse-pup.
Rebound firing of action potentials following hyperpolarization, the signature firing pattern of RNT neurons during sleep, was also reduced.
Also, NSCs and their progeny on graphene substrates exhibited increased firing of action potentials during development compared to controls.
Central nucleus of the amygdala neurons were depolarized by a current injection to evoke the sustained firing of action potentials.
Recordings were made from the regular firing of action potentials from the oculomotor or trochlear nuclei of two macaque monkeys while stimulating at a variety of locations.
McLean, M. & Macdonald, R. Sodium valproate, but not ethosuximide, produces use- and voltage- dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture.
... Simulation studies in a modified Hodgkin-Huxley neuron and network unraveled that the reduction of slowly inactivating IK DR) resulted in membrane depolarization accompanied by termination of the firing of action potentials in a stochastic manner.
Researchers have reported increased fluctuation power and slowed time-scales prior to the firing of action potentials in a squid giant axon [9], and in simplified point models of resonator and integrator neuron types [10].
This would be expected to hyperpolarize the RMP, thereby reducing spontaneous firing of action potentials in the clock neurons in which it is expressed (14,25).
To test whether changes in fluorescence correlated with firing of action potentials (APs), we infected dissociated mouse superior cervical ganglion (SCG) neurons and recorded action potentials with sharp electrodes while imaging corresponding fluorescence changes with two-photon microscopy.
