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If the population of labs is small, a finite population adjustment is possible [ 21], but rarely used in practice.
After obtaining the efficiency scores from the pooled DEA model, we constructed a random-effects Tobit regression model with finite population adjustment as the second stage of the efficiency analysis [ 14, 26, 27].
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Toward that end, in this study we evaluate precision and bias of the original single-sample method for estimating Ne– that based on random linkage disequilibrium (LD) that arises by chance each generation in finite populations (Laurie-Ahlberg and Weir 1979; Hill 1981).
To counter this argument, we have to ask whether there is a more general way to determine the relevance of quasispecies theory to finite populations of RNA viruses.
The previous paragraphs show that on purely theoretical grounds, there is no reason to assume that quasispecies effects cannot play a role in finite populations of RNA viruses.
In summary, we currently have no evidence (theoretical or experimental) that contradicts the existence of quasispecies effects in finite populations of RNA viruses, but we also have no experimental evidence in favor of it.
Until we embrace the simple fact that the world is a finite place and as such can support a finite population, what the UN fears will only be the beginning.
It appears that inbreeding due to the finite population size of the OOA was also insufficient to meaningfully alter the allele frequency distribution or extent of LD.
We investigate the evolutionary dynamics of a finite population of sequences adapting to NK fitness landscapes.
Thus, while mutation and recombination can dampen the LD oscillations, finite population size counters this process.
The sampling proportion is used to adjust the finite population.
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